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adenoviral vector-based gene therapy. Nadofaragene firadenovec uses a recombinant adenovirus that encodes for interferon alpha-2b gene. Intravesical instillation of interferon alone for bladder cancer produced complete responses that were short lived in previous studies. Adstiladrin is also called nadofaragene firadenovec-vncg. Adstiladrin is a gene therapy that uses a non-replicating adenoviral vector (a modified virus that cannot multiply) to deliver a gene to bladder cells. This gene makes a protein called interferon alfa-2b, which activates the immune system to fight cancer cells. How do I
take it?
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